I've been to about maybe 4-5 conventions total. The last one I went to was MatsuriCon in Ohio and I had a blast!
Generally, when I do go to conventions, its VERY rare that I stay the entire weekend because staying in the hotels are expensive and I can only set aside so much money for anime merchandise and food. But overall, it's been worth it; going to panels to see my favorite voice actors, getting autographs, buying wall scrolls & fan-made stuff and meeting die-hard anime fans who are into the same stuff I am. XD