VN: It's so hard to pick just one among all the amazing works I've met in the past decade. I'd nominate Chaos;Child, ISLAND, Utawarerumono: Mask of Deception (I count it as a VN regardless of its RPG elements), Four Rhythms Across the Blue, and Senren*Banka. And finally I chose Senren*Banka because it brought me so much laughter, and the soundtrack is really awesome.
Anime: Little Witch Academia. Other nominees: Hyouka, Psycho-Pass (Season 1), Fune wo Amu, Zombie Land SAGA.
Manga: And Yet the Town Moves (half of the volumes are published in 2010s so I think it's fine). I was considering Attack on Titan but I picked a more joyous one at last. I also like Ayakashi Hisen, and I even bought the folding fan from the manga in Kyoto.
Game: Sekiro. Miyazaki-sensei is the best.