That depends if I like the system of the game or not. Say Eien no Aselia- it's not grindy, but if it were, I wouldn't be able to play it, since I dislike the battle system. However, I loved Kamidori's system, and I grinded to get every character to level 99, get all of the artifacts, etc (Mylen's artifact took me about 20~30 replays through the same dungeon, and that wasn't even the one artifact I spent the most time to get).